Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Assessment of Color Changes in Vita 3D-Master Shade Guide after Sterilization and Disinfection4853826510.22038/jdmt.2017.8265ENHossein Dashti1. Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
2. Assistant Professor of Prosthetic Department, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranAzizollah Moraditalab1. Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
2. Assistant Professor of Prosthetic Department, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranMohammadreza Mohammadi1. Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
2. Assistant Professor of Prosthetic Department, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranHamidreza Rajati Haghi1. Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
2. Assistant Professor of Prosthetic Department, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranJournal Article20161015<strong>Purpose:</strong>Dental shade guides are commonly used for color determination and should be disinfected and sterilized. The purpose of this study was to evaluate the color change of Vita 3D Master shade tabs after disinfection and sterilization. <strong>Material and methods:</strong>Overall, 98 samples (shade tabs) were randomly selected from 14 new, unused Vita 3D sets, including the following shades: 2M1, 3L1.5, 3M1, 3M2, 3M3, 3R1.5 and 4M1. In each set, values of 2, 3 and 4, chroma of 1, 2 and 3 and hue were selected for the comparison of different shades. All tabs were measured using the Vita Easyshade device at baseline. The first group was disinfected with Deconex and the second group was sterilized by autoclaving in a simulated annual application. All the tabs were measured again using the same device. This process was repeated to simulate 2 and 3 years of usage. Statistical analysis was conducted by repeated measures analysis of variance (ANOVA) and independent t-test and paired sample t-test. <strong>Results:</strong>In the disinfected group, we observed significant differences in value and chroma in all periods (p˂0.001). However, hue showed no significant difference after the first year of simulated treatment (p=0.527), though it was significantly different in the second and third simulations (p˂0.001). In the sterilized group, all variables showed a significant difference for each year (p˂0.05). Considering total color difference (ΔE), there was a significant difference between the two groups in the first, second and third simulated years; ΔE increased in the sterilized group more than in the disinfected samples (p˂0.001). <strong>Conclusions:</strong><em> </em>The color change of shade tabs was significant both after disinfection by a chemical solution and by sterilization through autoclaving. However, although disinfectants may not have a clinically important effect, sterilization should be considered as an interfering factor during color-matching procedure.Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Evaluating the effect of ceramic veneer thickness on degree of conversion in three luting resin cements5460850810.22038/jdmt.2017.8508ENNafiseh ElmamoozAssistant professor, Oral and dental disease research center, Kerman University of Medical sciences, Kerman, Iran.Ali EskandarizadehAssociate professor, Oral and Dental Disease Research Center, Kerman University of Medical Sciences, Kerman, IranElina RahmanianResident of Operative Dentistry, Oral and Dental Disease Research Center, Kerman University of Medical Sciences, Kerman, IranShahriar Sarvareh AzimzadehResident of Orthodontics, Oral and Dental Disease Research Center, Kerman University of Medical Sciences, Kerman, IranJournal Article20170129compare the effect of different ceramic thicknesses on degree of conversion (DC) of 3 light-cured resin cements. <strong>Methods:</strong> In this experimental in-vitro study, the degree of conversion of three light-cured resin cements, Variolink Veneer (Ivoclar, Liechtenstein), RelyX Veneer (3M ESPE, USA) and Choice2 (Bisco, USA) were evaluated beneath feldespatic ceramic discs (Vita VMK Master) with a same shade, 2m2, in different thicknesses (0.5, 1, 2 and3 mm) using FTIR. The light curing unit used was Optilux 501, with an intensity of 600 mW/cm<sup>2</sup> and exposure duration of 40 seconds. Three specimens of each cement group were examined in each condition. The obtained data was submitted to Kolmogorov-Smirnov and also checked for absence of skewness and kurtosis for normal distribution. After that, ANOVA test was used for comparison between experimental groups (Tukey HSD).<strong> Results:</strong> In all the three used cements, DC decreased as ceramic thickness increased. This reduction was not significant when using 0.5 and 1 mm ceramic discs, however, it was significant between 1, 2, and 3mm discs(p<0.05). There was no difference within the cements’ DC when exposed through ceramic discs of 0.5, 1, and 2mm, but the Rely X Veneer cement had a lower DC compared to Variolink Veneer and Choice2 when the thickness increased to 3mm(p<0.05). <strong>Conclusion:</strong> It is not advisable to use light-cured resin cements beneath 3 mm thick ceramics and the use of Rely X Veneer is not recommended as the ceramic thickness increases.<br /> <br /> <br /> Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Evaluation of Diagnodent Accuracy in Detecting Approximal Caries in Primary Molars6166849110.22038/jdmt.2017.8491ENZahra BahrololoomiAssociate Professor of Pediatric Dentistry, Faculty of Dentistry, Shahid Sadoughi University of Medical Science, Yazd, IranBentolhoda VarkeshPedodontistFatemeh EzodiniProfessor of Maxillofacial Radiology, Faculty of Dentistry, Shahid Sadoughi University of Medical Science, Yazd, IranShiva ZamaninejadAssistant Professor of Pediatric Dentistry, Faculty of Dentistry, Golestan University of Medical Science, Gorgan, IranJournal Article20170625<strong>Introduction:</strong> Detection of caries lesions on approximal surfaces of posterior teeth is difficult, since wide contact points hamper direct visual inspection. Due to the importance of the early detection of dental caries, the aim of this study is to compare the performance of different methods (visual, bitewing radiography and DIAGNOdent) in detecting approximal caries in primary molars.<strong> Methods:</strong> Thirty six children were selected from patients referred to the pediatric dentistry department of Shahid Sadoughi University of Medical Sciences, Yazd, Iran<em>.</em> Two examiners evaluated 229 approximal surfaces of primary molars using: visual inspection, radiography and a pen-type laser fluorescence device (DIAGNOdent) for the presence of proximal caries. The surfaces were evaluated by 2 other examiners for the presence of white spots or cavitations. Sensitivity, specificity and accuracy (percentage of correct diagnosis) were calculated for each method. The area under the receiver-operating characteristics curve (A z) was calculated for DIAGNOdent device. The inter-examiner reproducibility was calculated using the intra-class correlation coefficient (ICC values) for laser Fluorescence and agreement coefficient for visual and radiographic methods<em>.</em><strong>Results:</strong> At white-spot threshold, a DIAGNOdent device presented better performance. At cavitation threshold the radiographic method demonstrated higher sensitivity than visual inspection and DIAGNOdent device<em> .</em>In this threshold, all methods presented high specificities<br /> <strong>Conclusions:</strong> A DIAGNOdent device performs better in white spot threshold. However, radiography shows better performance in detecting more advanced approximal caries lesions.<br /> <br /> Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Knowledge and Attitude of Primary School Staff to Management of Dental Trauma in North-east of Iran in 20156772849310.22038/jdmt.2017.8493ENArmita RouhaniDepartment of Endodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranTaraneh MovahhedOral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Pediatric Dentistry, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranYones MohitiPostgraduate Student of Oral and Maxillofacial Radiology, Babol University of Medical Sciences, Babol, IranElham BanihashemiUndergraduate Student of dentistry, Mashhad University of Medical Sciences, Mashhad, IranMajid AkbariDepartment of Restorative Dentistry, Mashhad University of Medical Sciences, Mashhad, IranJournal Article20170129<strong>Introduction:</strong> The purpose of this study was to assess the level of primary Knowledge among school staffs in Iran with regards to the immediate management of dental trauma. <strong>Methods:</strong> The data, from 160 participants, were collected using questionnaire, which surveyed staff’s background, attitude and knowledge of dental trauma management.<br /> <strong>Results:</strong> The total number of school staff who responded to all of the questions in the questionnaire was 138; the response rate was 86%. 91.3% of the participants had more than 10 years of teaching experience. Only 24 cases (17.4%) have participated in training courses in regards to the dental trauma. 46.4% of the participants estimated their level of knowledge regarding the dental trauma as moderate and 42.8% as low and 7.2% without knowledge, however, 56.5% of them were highly interested in attending the training courses. Overall, the teachers’ knowledge on emergency management of the dental trauma cases presented in this study was deficient, especially in avulsed tooth management. Chi-square test showed that there was no statistically significant difference in the responses to the knowledge part of the questionnaire on age, gender, teaching experience and responsibility in school. <strong>Conclusion:</strong> The present report indicated the lack of knowledge among school staff on dental injuries managements. Organizing educational courses to improve the knowledge and awareness of school staff, as the first encounters of dental trauma in schools, seems necessary.<br /> <strong> </strong><br /> Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Consistent absence of BRAF mutations in salivary gland carcinomas7378831910.22038/jdmt.2017.8319ENNooshin MohtashamDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranHossein AyatollahiDepartment of Hematology and Blood Bank, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNarges GhaziDental Research Center, Mashhad University of Medical Sciences, Mashhad, IranAmirhossein JafarianDepartment of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranAzam RoshanmirDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Golestan University of Medical Sciences, Golestan, IranJournal Article20161218<strong>Introduction:</strong> Malignant salivary gland tumors are rare entities. Despite advances in surgery, radiation therapy and chemotherapy, the rate of the mortality and five-year survival has not been improved markedly over the last few decades. The activation of EGFR- RAS-RAF signaling pathway contributes to the initiation and progression of many human cancers, promising a key pathway<br /> for therapeutic molecules. Thus, the objective of this study was to evaluate BRAF mutations in salivary gland carcinomas. <strong>Methods:</strong> We designed PCR- RFLP (Polymerase Chain Reaction -Restriction Fragment Length Polymorphism) and screened 50 salivary gland carcinomas (SGCs) including mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (AdCC) and polymorphous low grade adenocarcinoma (PLGA) for the BRAF V600E mutation. <strong>Results:</strong> PCR-RFLP analyses demonstrated no mutation in BRAF exon 15 for SGC samples at position V600, which is the most commonly mutated site for BRAF in human cancer.<strong> Conclusions:</strong> According to our results SGCs didn’t acquire BRAF mutations that result in a constitutive activation of the signaling cascade downstream of EGFR, hence SGCs can be a good candidate for anti EGFR therapies.Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Revascularization procedure in an open apex tooth with external root resorption: A case report7982849010.22038/jdmt.2017.8490ENMahsa DastpakPostgraduate Student of Endodontics, Mashhad University of Medical Sciences, Mashhad, IranHamid JafarzadehAssociate Professor, Department of Endodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran0000-0001-5318-7129Elham NajafiPostgraduate Student of Endodontics, Mashhad University of Medical Sciences, Mashhad, IranJournal Article20170104External inflammatory root resorption (EIR) represents a challenge in endodontic practice. EIR commonly occurs after dental trauma that results in periodontal ligament injury, pulp necrosis and subsequent infection. Treatment of EIR is based on disinfecting the root canal system through chemomechanical procedures and then filling it with calcium hydroxide or triple antibiotic paste. Dental trauma commonly occurs in young patients whose teeth are not fully formed and have thin dentinal walls and open apices. Revascularization therapy has proven to be suitable for treatment of root canals of teeth with pulp necrosis and open apices. This case report presents successful revascularization treatment of a permanent immature tooth with external root resorption and chronic apical periodontitis. The tooth was treated by the protocol suggested by the American Association of Endodontics (AAE), consisted of disinfecting the root canal system, filling it with blood clot and sealing the root canal with mineral trioxide aggregate followed by bonded resin restoration. The symptoms disappeared, the size of the periapical lesion reduced and the tooth was asymptomatic during the 12 month follow up period.<br /> <br /> <br /> Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Synchronization of Calcifying Odontogenic Cyst and Aneurysmal Bone Cyst: A Case Report8388794710.22038/jdmt.2016.7947ENJahanshah Salehinejad1.Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran 2.Professor, Oral and Maxillofacial Pathology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.Baratollah ShabanAssistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.Tahere MehriPostgraduate Student, Department of Oral and Maxillofacial Radiology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.Azam RoshanmirAssistant Professor , Oral and Maxillofacial Pathology, Dentistry Research Center, Golestan University of Medical Sciences, Gorgan, Iran.Journal Article20160529Although aneurysmal bone cysts and calcifying odontogenic cysts accompanied with other lesions are reported in the literature, the simultaneous occurrence of these two distinct lesions has not been reported. To the best of our knowledge, this is the first report describing co-occurrence of these two lesions located in the left mandibular ramusin a 36-year-old woman.<br /> <br /> <br /> Mashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41506220170601Wegener Granulomatosis with Oral Involvement as Primary Manifestation: A Case Study8995831810.22038/jdmt.2016.8318ENPegah Mosannen Mozaffari1. Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2.Associate Professor of Oral Medicine, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranMahdokht Rashed1.Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2.Assistant Professor of Oral and maxillofacial medicine, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranAbbas Javadzadeh1.Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2.Associate Professor of Oral Medicine, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranMehrdad RadvarProfessor of Periodontitis, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranNooshin Mohtasham1.Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2.Professor of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diseases Research Center, Department of Oral and Maxillofacial Pathology, Mashhad University of Medical Sciences, Mashhad, IranSedigheh Modarres MousavyPost Graduate Student of Oral and Maxillofacial Medicine, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, IranJournal Article20160618<strong>Introduction:</strong> Wegener Granulomatosis is a rare multisystemic disease with an unknown cause, characterized by necrotic granulomatous lesions in respiratory tract, systemic vasculitis in small arteries and veins and necrotizing glomerulonephritis. Wegener can affect any organ including kidneys, eyes or other organs but classically affects upper and lower respiratory tract. One of the rare but important signs of this disease is oral involvement, generally occurring in 6-13% of patients, however, oral involvement as the primary manifestation of disease, occurs in only 5-6% of cases. The most common oral manifestation is strawberry gingivitis.<strong> Patients:</strong> Our patient was a 35 year-old man with gingival bleeding during brushing which began approximately 45 days before referring to the department of oral and maxillofacial diseases, Mashhad Dental School. In intraoral examination, his gingiva had a papillomatous appearance and was purple in color (strawberry appearance). Due to the presence of strawberry appearance in absence of plaque, primary diagnosis of Wegener granulomatosis was established and the patient was referred for histopathological evaluation. In laboratory tests, C-ANCA was positive and P-ANCA was negative. Finally, diagnosis of Wegener granulomatosis was confirmed and his treatment was started. Rheumatologic condition of patient's lungs was evaluated by chest X-ray and CT-scan and blood tests, biochemistry tests and urine analysis were performed for the patient. He did not have pulmonary or renal involvement. In our study, the patient was followed up after 1, 2 and 11 months from the first visit.<strong> Discussion:</strong> Up to now, few reports have been published on Wegener disease with oral involvement and in most of these articles, Wegener was diagnosed after respiratory symptoms and kidney or other organs involvement. Only in few studies was Wegener diagnosis confirmed on the basis of oral symptoms and gingival involvement. Immediate and aggressive administration of immunotherapy treatments are required due to the fatal nature of the disease as the survival rate of patients with untreated WG is low and 90% of these patients die within 1 year after respiratory or kidney involvement .