TY - JOUR ID - 9416 TI - Comparison of C - reactive protein Levels in Chronic Periodontitis Patients with Normal Subjects JO - Journal of Dental Materials and Techniques JA - JDMT LA - en SN - 2322-4150 AU - Ansari Moghadam, Somaye AU - ZadFattah, Siavash AU - Risbaf Fakour, Sirous AU - Ansari Moghaddam, Alireza AU - Naebi, Mohammad AD - Assistant Professor,Periodontology Department, Oral and Dental Disease Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran AD - General Dentists, Zahedan University of Medical Sciences, Zahedan, IR Iran AD - Assistant Professor,Oral and Maxillofacial Surgery Department, Oral and Dental Disease Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran AD - Associate Professor,Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran AD - Student of Dentistry, Tabriz University of Medical Sciences, Tabriz, IR Iran 3DMD, private practice Y1 - 2017 PY - 2017 VL - 6 IS - 4 SP - 181 EP - 185 KW - LATEX – high sensitivity KW - C – reactive protein KW - systemic inflammation KW - chronic periodontitis KW - healthy subjects DO - 10.22038/jdmt.2017.9416 N2 - Background: Chronic periodontitis causes systemic inflammation and increases C-reactive protein (CRP). CRP has been implicated as a possible mediator of associating periodontitis and several systemic diseases. The aim of the present study was to investigate systemic levels of CRP in patients with chronic periodontitis in comparison to periodontally healthy individuals.    Materials and methods: A total of 80 individuals were included in this study. 40 patients with severe chronic periodontitis aged 40, and 40 sex matched periodontally healthy subjects were recruited from the patients attending Dpartment of Periodontics, Faculty of Dentistry, Zahedan. Body Mass Index (BMI) was under 25 kg/m2 in all the patients and controls. Peripheral blood samples were taken and CRP levels were estimated in serum samples using the C - reactive protein – hs (CRP-hs) LATEX – High sensitivity (Biosystem S.A).  Result: CRP levels in women in the test group (3.64 +- 2.77 mg/l) was significantly higher than the women in the control group (p < 0.001); however, the difference between males in the two study groups was not significant (p=0.13). Conclusion: Periodontitis results in higher systemic levels of CRP. Elevated inflammatory factor may increase inflammatory activity in atherosclerotic lesions and potentially increase the risk for cardiovascular events.    UR - https://jdmt.mums.ac.ir/article_9416.html L1 - https://jdmt.mums.ac.ir/article_9416_861f53951d9a4662c3648e43908c774a.pdf ER -