TY - JOUR ID - 13379 TI - Evaluation of Mechanical Properties of Polyethylene‌‌ Glycol/ Dextrane Methacrylate / Maleic Acid Copolymer as a Biological Scaffold JO - Journal of Dental Materials and Techniques JA - JDMT LA - en SN - 2322-4150 AU - Safari, Noha AU - Esfahanian, Vahid AU - Kolahdoozan, Majid AU - Khosravi, Armin AD - Dentist AD - Associate Professor, Department of periodontics, School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran AD - Associate Professor, Department of biochemistry, Islamic Azad University, Shahreza Branch, Shahreza, Isfahan, Iran AD - Postgraduate Student, Department Of periodontics, School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran Y1 - 2019 PY - 2019 VL - 8 IS - 3 SP - 143 EP - 148 KW - Maleic acid KW - polyethylene glycol KW - Dextran methacrylate KW - Mechanical properties KW - Biodegradability DO - 10.22038/jdmt.2019.13379 N2 - Abstract Introduction: The use of membranes and transplant materials as scaffolds in periodontal regenerative surgeries is gaining an increasing application for restoring the structure and function of lost tissues. The present study aimed to evaluate the mechanical properties of PEG/MA (Polyethylene glycol/Maleic Acid) copolymer as a bioscaffold. Methods: In this experimental laboratory study, a hydrogel scaffold was first manufactured of PEG/MA copolymer. Different hydrogel concentrations were prepared using visible light through changing concentrations of C2/1, c1/1 and C1/2 (C ⅟2, C ⅟1 and C2/1) of PEG/MA copolymer to those of dex-METH (dextran-methacrylate). Then, 57 samples were selected, 27 and 30 of which were related to degradation rate and solidification tests, respectively. The samples were examined in three triplet groups within three time periods to test the degradation rate. Five quintuplet groups were also classified to measure the tensile and compressive strengths using a microtensile device. Data were analyzed by one-way/two-way ANOVA and Tukey test. Results: Both the concentration of PEG/MA copolymer (P<0.007) and sample incubation duration (P<0.001) affected sample degradation rates, with C 2/1 group yielding the lowest degradation rate. Furthermore, mean values of tensile strength (P <0.04) and compressive strength (P< 0.001) were significantly different among the three groups.  Conclusion: A change in the proportion of the copolymer ingredients can affect the mechanical properties and destruction rate of the substance. Due to slow degradation rate and high tensile strength, a concentration of 1/2 is more appropriate to be used as a membrane for covering bone loss.     UR - https://jdmt.mums.ac.ir/article_13379.html L1 - https://jdmt.mums.ac.ir/article_13379_c708b68df52574dfd767ebe3bbf77874.pdf ER -