TY - JOUR ID - 10023 TI - Metastatic Tumors to Craniofacial Skeleton: Analysis of Two Cases and Review of the Literature JO - Journal of Dental Materials and Techniques JA - JDMT LA - en SN - 2322-4150 AU - Dalband, Mohsen AU - Shahidi, Shoaleh AU - Gholami, Mahdi AU - khayati, Adell AD - Associate Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Science, Tehran, Iran AD - Professor, Biomaterial Research Center, Department of Oral and Maxillofacial Radiology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran AD - Oral & Maxillofacial Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran AD - Assistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Kurdestan University of Medical Science, Sanandaj, Iran Y1 - 2018 PY - 2018 VL - 7 IS - 1 SP - 43 EP - 48 KW - metastatic tumor KW - Prostate cancer KW - Adenocarcinoma KW - craniofacial skeleton DO - 10.22038/jdmt.2018.10023 N2 - Craniofacial skeletal metastasis is a rare presentation of advanced prostate cancer. This is a report of a 69-year-old man who presented with numbness of the right lower lip and recently ill-fitting lower denture. Based on the medical history of benign prostate hyperplasia (BPH) and suspicion of a metastatic tumor, prostate core needle biopsy was performed. Histology of the prostate biopsy confirmed an adenocarcinoma with Gleason Score of 6/10. The diagnosis of metastatic prostate adenocarcinoma was established by incisional biopsy from the mandibular lesion. Androgen deprivation therapy (ADT) was administered along with bilateral orchidectomy and radiotherapy. He had a significant resolution of trigeminal nerve palsy and the other symptoms at subsequent follow-ups, but after 18 months passed away. The second case was a 65-year-old man with a history of prostate cancer since 5 years ago. He complained of painful swelling in the right side of the face. Radiographic evaluation revealed new bone formation in right mandibular ramus and condylar process as well as the left temporoparietal region. Incisional biopsy from mandibular lesion revealed metastatic prostate adenocarcinoma. Palliative radiotherapy for increasing quality of life started for the patient but he died after 9 months. The related literatures were reviewed.       UR - https://jdmt.mums.ac.ir/article_10023.html L1 - https://jdmt.mums.ac.ir/article_10023_72535f950baa198274157eec0f5512a2.pdf ER -