TY - JOUR ID - 7375 TI - Endodontic Therapy of the Periapical Lesion in the Anterior Mandibular in a Patient with Tricho-Dento-Osseous Syndrome and Consumer of Immunosuppressive Drug: A Case Report JO - Journal of Dental Materials and Techniques JA - JDMT LA - en SN - 2322-4150 AU - Moghim Farooji, Elaheh AU - Kazemi, Zeinab AU - Moradi, Saeed AD - Department of Endodontics, Dental School, Hormozgan University of Medical Sciences, Bandarabbas, Iran AD - Postgraduate Student of Endodontics, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran AD - Professors of Endodontics, Dental Materials Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Y1 - 2017 PY - 2017 VL - 6 IS - 1 SP - 44 EP - 47 KW - Endodontic therapy KW - Tricho-Dento-Osseous syndrome KW - Immunosuppressive drug KW - D-penicillamine DO - 10.22038/jdmt.2016.7375 N2 - Tricho-Dento-Osseous syndrome is a rare autosomal dominant disorder. Immunosuppressive drugs, though critical to the treatment, have undesirable effects on patient's healing process. This is a case report of a 10-year-old female, suffering from Tricho-Dento-Osseous syndrome who was under treatment with penicillamine. As the dental treatment was sought too late, both central and lateral incisors on the right side of mandible had severe enamel hypoplasia and tooth necrosis was evident. A large lesion was found in anterior mandible. After proper treatment of the teeth with appropritately considering the systemic condition of the patient, the favorable result was achieved.   UR - https://jdmt.mums.ac.ir/article_7375.html L1 - https://jdmt.mums.ac.ir/article_7375_b2248fe6cb4e4ee74dcf4920866efd13.pdf ER -